Horrible treatment (radiation) associated epithelial changes in duodenal mucosa. The p53 can be ignored, probably reflecting upregulation rather thana mutational event. The same can be seen in the stomach. Hutchings DA, Salimian KJ, Waters KM, Birkness-Gartman JE, Voltaggio L, Assarzadegan N, Huang J, Lin MT, Singhi AD, Montgomery EA. Aberrant p53 Expression in Gastric Biopsies and Resection Specimens Following Neoadjuvant Chemoradiation: A Diagnostic Pitfall. Int J Surg Path

An example of crystal storing histiocytosis; the patient needs to be evaluated for a plasma cell disorder or other lambda-restricted B cell neoplasm. Arnold CA, Frankel WL, Guo L, Krishnan C, Pfeil S, Schumacher M, Voltaggio L, Yearsley MM, Chen W. Crystal-storing Histiocytosis in the Stomach: A Clue to Subtle Hematolymphoid Malignancies. Am J Surg Pathol. 2018 Oct;42(10):1317-1324. PMID: 29878935. Case by Dr. Elizabeth Montgomery, Clinical Professor, Vice Chair of Faculty De