It is rare in the tubular gastrointestinal tract, but globular amyloid is associated with light chain restriction. There is no neoplasm here, but the patient should be investigated for a plasma cell disorder. www.innovativesciencepress.com Hemmer PR, Topazian MD, Gertz MA, Abraham SC. Globular amyloid deposits isolated to the small bowel: a rare association with AL amyloidosis. Am J Surg Pathol. 2007 Jan;31(1):141-5. PMID: 17197930. Case by Dr. Elizabeth Montgomery, Clinical

Pleomorphic hyalinizing angiectatic tumor was described years ago and is usually indolent; rare progression to high grade sarcoma is known. Smith ME, Fisher C, Weiss SW. Pleomorphic hyalinizing angiectatic tumor of soft parts. A low-grade neoplasm resembling neurilemoma. Am J Surg Pathol. 1996 Jan;20(1):21-9. PMID: 8540605. Case by Dr. Elizabeth Montgomery, Clinical Professor, Vice Chair of Faculty Development & Mentoring, Director of Surgical Pathology Fellowship Training Pr