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It is rare in the tubular gastrointestinal tract, but globular amyloid is associated with light chain restriction. There is no neoplasm here, but the patient should be investigated for a plasma cell disorder. www.innovativesciencepress.com


Hemmer PR, Topazian MD, Gertz MA, Abraham SC. Globular amyloid deposits isolated to the small bowel: a rare association with AL amyloidosis. Am J Surg Pathol. 2007 Jan;31(1):141-5. PMID: 17197930.

Case by Dr. Elizabeth Montgomery, Clinical Professor, Vice Chair of Faculty Development & Mentoring, Director of Surgical Pathology Fellowship Training Program, Co-Director, Pathology Reference Services, and Editor-In-Chief at Innovative Science Press.


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