Please ensure Javascript is enabled for purposes of website accessibility
Search

Case of the Week

This is a needle biopsy from a pancreatic head mass. What is your diagnosis?

Answer: Pancreatic Acinar Cell Carcinoma


Comment: The trypsin expression is stronger in the acini than in the neoplasm. It is easy to mistake these neoplasms for pancreatic ductal adenocarcinoma if the diagnosis is not considered. Similarly, it is easy to confuse these tumors with neuroendocrine neoplasms. To compound the mimicry, acinar cell carcinomas can express synaptophysin. The best marker is probably BCL10 (not depicted).


PMID: 27320062

PMID: 25266736

PMID: 19066953


Case was provided Dr. Elizabeth Montgomery, Editor-in-Chief of the Pathology Survival Guides at Innovative Science Press, and professor of pathology and Vice Chair of Anatomic Pathology at the University of Miami.


Our Survival Guide to Pancreas Pathology is forthcoming, but you can check out our other titles at:


www.innovativesciencepress.com

info@innovativepathologypress.com

1-703-350-4308/703-340-3198

909 views0 comments

© 2020 by Innovative Science Press

Accessibility