Case of the Week

History: This is a skin biopsy from the breast of a 70 year old woman. What is your interpretation?

Diagnosis: This angiosarcoma arose in the skin overlying the breast in a patient who was status post therapeutic radiation for mammary carcinoma. The immunohistochemical stain is a CD31.

Comment: This lesion arose just 3 years after radiation, which is early but not unprecedented.

PMID: 30251277

This case was provided by Dr. Elizabeth Montgomery, Professor of Pathology and Vice Chair of Anatomic Pathology at the University of Miami, and the Editor-in-Chief of Innovative Science Press. You can check out her GI and Soft Tissue volumes as well as our other titles: Liver, Endocrine, Dermpath, Prostate, Lymph Node and more at:

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