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This small intestinal gastrointestinal stromal tumor (GIST) has invaded the mucosa, a feature indicating aggressive behavior. This neoplasm was widely metastatic despite neoadjuvant targeted therapy. A mitosis is indicated (arrow).

Case provided by Dr. Elizabeth Montgomery, Clinical Professor, Vice Chair of Faculty Development & Mentoring, Director of Surgical Pathology Fellowship Training Program, Co-Director, Pathology Reference Services, and Editor-In-Chief at Innovative Science Press.

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